A Research Agenda for Curing Chronic Hepatitis B Virus Infection
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A Research Agenda for Curing Chronic Hepatitis B Virus Infection

There is a growing interest in the discovery and development of new therapeutics that will cure chronic hepatitis B virus (HBV) infection, due to the recent establishment of new cell culture–based and small animal–based models. These new systems create unprecedented opportunities to study the entire viral life cycle and to search for vulnerabilities that can be exploited for curative purposes. Here, we propose a scientific pathway that we believe will lead to the development of curative therapies for chronic HBV infection and its associated diseases.

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