Increasing Awareness and Treatment Competencies For Practicing Clinicians
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Increasing Awareness and Treatment Competencies For Practicing Clinicians

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Hepatitis Delta: Increasing Awareness and Treatment Competencies For Practicing Clinicians

  • HDV is underdiagnosed but prevalent in HBV infected patients
  • HDV has poor testing frequency and very low linkage to care
  • All HBsAg+ patients should be tested for HDV by total antibody testing and linked or reflexed to HDV RNA quant by PCR
  • HDV is in need of rapid test or POC tests on the global market
  • Best current treatment is INF with MVR rate of 20%, this does not define cure of HDV
  • Major need for new therapies to result in at least a 2 log reduction of viral load = reset of disease activity
  • New HDV therapies will have MVR of 40% with additional 20% with ”reset” of virus levels by 2 logs
  • Primary care clinicians can play a vital role in diagnosis and treatment

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