On-treatment risks of cirrhosis and hepatocellular carcinoma
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On-treatment risks of cirrhosis and hepatocellular carcinoma

On-treatment risks of cirrhosis and hepatocellular carcinoma among a large cohort of predominantly non-Asian patients with non-cirrhotic chronic hepatitis B

Chronic hepatitis B (CHB) remains a leading cause of liver-related morbidity and mortality worldwide, with nearly 300 million individuals affected globally.1,2 Existing studies have reported on disparities in the CHB cascade of care, with gaps in timely diagnosis and linkage to care, as well as delays in timely initiation of antiviral therapy. In 2016, it was estimated that approximately 10% of all individuals with CHB worldwide were diagnosed, and only 5% of individuals with CHB eligible for treatment actually received antiviral therapy.2 In the US, the prevalence of CHB may be as high as 2.4 million, and similar disparities in the CHB cascade of care have been reported.

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