THE PBC FOUNDATION STRONGLY URGES ALL PEOPLE WITH PBC AND THEIR FAMILIES TO FOLLOW THE NATIONAL GUIDELINES
There is a great spectrum of disease amongst people with PBC: most will have early disease and the liver is functioning normally. Others will have advanced fibrosis and some may have cirrhosis. Others will have had a transplant which may be associated with recurrence of PBC in the graft. Some will be taking immunosuppressive medication (such as prednisolone, azathioprine, mycophenolate, cyclosporine or tacrolimus). Some will have also other conditions such as diabetes or lung disease. There is some evidence that the outcome of Covid infection in those with advanced cirrhosis (of all causes) is worse than in those without cirrhosis. There is less strong evidence that those who are post-transplant may have worse outcomes when infected.