Genotype Documentation Fact Sheet - 2023
Hepatitis C genotype testing is a blood test that determines the genotype or “strain” of hepatitis C virus. There are six major HCV genotypes in the world. Genotypes 1, 2, and 3 are most common in the United States.
In the past, prior to the advent of pan-genotypic treatment regimens, genotype testing was an important step to determine what course of treatment would be most effective. Now, genotype testing isn’t necessary, because the recommended regimens are pan-genotypic and appropriate for any patient who qualifies for simplified treatment. While genotype testing may be situationally useful on a case-by-case basis when retreating patients to distinguish between treatment failure and reinfection, consideration should be given to whether cost and delays in care outweigh the benefit of ordering a genotype test.