HDV 101 - Hepatitis B ECHO
HDV 101 - Hepatitis B ECHO
Deck Summary
- Regardless of patient backgrounds or characteristics, all HBsAg+ individuals may be affected or infected by hepatitis delta
- Prevalence estimates for hepatitis delta are inaccurate due to insufficient data
- HDV requires the presence of HBV to enter hepatocytes and replicate, and can be acquired simultaneously with HBV (coinfection) or after CHB has been established (superinfection)
- Chronic hepatitis delta leads to rapid progression of liver disease, increasing the risk of cirrhosis, decompensated cirrhosis, liver transplant, HCC and mortality compared with HBV monoinfection
- Patients with hepatitis delta may experience decreases in quality of life, and may also face barriers to care
- All patients with hepatitis delta should be on nucleoside treatment to suppress HBV DNA
- New treatment is available in the EU and Pending FDA approval in the US Bulevirtide