Immunotolerant OLD name - New Name Chronic Infection HBV
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Immunotolerant OLD name - New Name Chronic Infection HBV

Treatimmunotolerant HBeAgpositive patients Summary

  • The natural history is not well defined at individual level
  • Progression of liver disease and HCC are not rare complications
  • Compliance to “wait and see” strategy is quite low
  • Effective and safe NUC with low cost are available (generics)
  • Established indications to NUC therapy: Immunosuppression, pregnancy, extrahepatic manifestations, HCWs, to reduce infectivity
  • Additional indications to NUC therapy: Age (>30), fibrosis, family history of HCC

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