Re: Removal of Vemlidy from CVS Health Formularies

Letter: Re: Removal of Vemlidy from CVS Health Formularies
Dear Mr. Joyner, Dr. Compton-Phillips, and Mr. DeVaney,
We have been made aware that Aetna CVS Health and CVS Caremark are instituting changes to their formulary plan and removing Vemlidy (tenofovir alafenamide, TAF) as a covered medication for treating chronic hepatitis B effective January 1st, 2026.
We, as caregivers and clinical thought leaders, ask that CVS Health add tenofovir alafenamide (TAF, Vemlidy) back onto its treatment formulary for hepatitis B, allowing the decision regarding hepatitis B treatment to be left to healthcare providers and their patients. Every patient with hepatitis B should have access to the best treatment that meets their individual needs. Healthcare providers, with intimate knowledge of their patients’ healthcare needs, should have all current, front-line treatments available to prescribe.
For many people with hepatitis B, TAF is the best and only option for treatment. TAF is less likely to cause adverse effects on bone mineral density and renal dysfunctions than tenofovir disoproxil fumarate (TDF). By removing Vemlidy from the formulary plan, CVS Health is implementing a significant barrier to thousands of Americans at risk for these complications who may need and/or rely on this drug to manage their hepatitis B. The decision to remove Vemlidy as an option for individuals forces “non-medical switching,” where a patient must change medications for reasons other than their health. Non-medical switching is associated with poor health outcomes, and higher costs for patients, thereby decreasing accessibility of medications. A 2019 study by the Alliance for Patient Access found that 1 in 10 patients reported being hospitalized for complications after being switched off their preferred medication; and 40% stopped taking their medication completely. A 2017 study concluded that cost-motivated medication switches result in higher non-drug medical costs, such as doctor office visits, hospitalizations, and ER visits.
