Screening for Liver Disease:The work-up and diagnosis of acute and chronic liver disease 2025
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Screening for Liver Disease:The work-up and diagnosis of acute and chronic liver disease 2025

Screening for Liver Disease:The work-up and diagnosis of acute and chronic liver disease - 2025

Who should be tested for liver disease?

  • Symptom based
  • Risk based
  • Referral due to elevated liver tests on blood tests
  • Referral due to abnormal liver imaging

Consider Liver Disease Testing :

  • All patients with metabolic syndrome
    • Test for MASH and hemochromatosis
  • Patients with risk history, high risk sex or drug use, HCV HBV HIV
  • Immigrant populations; HBV HCV
  • Birth cohort: HCV
  • All adults: HCV HBV
  • Repeat HCV testing in high risk individuals
  • Repeat HBV testing
    • risk based annually after testing all adults
    • Children born to HBV+ mothers
  • Psychiatric disorders: Wilson Disease
  • Lung disease: Alpha-1
  • Autoimmune disease? Do AIH work up

Mandatory Liver Disease Testing :

  • Jaundiced patient
  • Large liver on physical exam
  • Signs of cirrhosis/CLD on PE
  • Abnormal liver imaging
  • History or current of abnormal liver tests
  • RUQ pain
  • Family history of liver disease

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